Experimental breast cancer treatment allows Florida woman to return to normal life

Phyllis Laccetti a participant in the TailorX breast cancer study at her home in Ossining NY

"Moving forward, when women are making this decision, this study will help us put it into perspective and give them better advice next week than we were able to give them last week", said Litton, who attended the American Society of Clinical Oncology conference in Chicago where the results were discussed.

The TAILORx study, led by the Montefiore Medical Centre in NY, found women older than 50 with this form of breast cancer and a score of up to 25 did not need chemotherapy.

"This is a major finding", said Dr Larry Norton, a breast cancer expert at Memorial Sloan Kettering Cancer Centre in NY, who helped organise the government-funded study more than a decade ago.

Several of the study authors consult for the company that makes the gene test or for breast cancer drugmakers.

"They were able to give the patient's own immune system a major boost".

What is less clear is whether chemotherapy will be of any benefit to the majority of patients who have a mid-range recurrence score.

But as the AP points out, in recent years, cancer treatment has been evolving and moving away from chemotherapy.

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"[The findings] are both important and significant, and also practice-changing", says, Dr. José Baselga, a medical oncologist and physician in chief at Memorial Sloan Kettering Cancer Center in NY, who was not involved with this research.

A doctor exams mammograms, as part of a regular cancer prevention medical check-up at a clinic in Nice, south eastern France. Exploratory analyses did suggest that the addition of chemotherapy was associated with some benefit for women 50 years of age or younger who had a recurrence score of 16 to 25, but not for those whose score 15 or lower.

"We are thrilled by this early finding, but we must remember that this type of immunotherapy remains an experimental approach that has a long way to go before it might be routinely available to patients". It was the women in the intermediate stages of 11-25 who oncologists often had differing views when prescribing standards of care.

This researchers split the middle-scoring group into two randomized subgroups: one treated exclusively with estrogen-blocking hormone therapy, and one with chemo combined with hormone therapy.

That's why it's great news to hear that doctors in the United States have just made an wonderful scientific breakthrough through, curing a woman who was in the advanced stages of the disease.

"Tumors grow more aggressively in premenopausal women, not just women under 50", Brawley said.

While chemo can be greatly helpful to some patients, it has a significant number of drawbacks and serious side effects.

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A woman with terminal breast cancer has been cured completely.

In a landmark first case, Judy Perkins was diagnosed with breast cancer and given only three months to live.

Rachel Rawson, clinical nurse specialist at Breast Cancer Care, said: "This life-changing breakthrough is absolutely wonderful news as it could liberate thousands of women from the agony of chemotherapy".

A high recurrence score, above 25, means chemo is advised to ward off a recurrence, while a low score, below 10, means it is not. And even though Oncotype DX came out in 2004, the experiments that showed chemotherapy helping people with some results of the tests weren't published until 2015.

All of the women in the study, called the Trial Assigning Individualized Options for Treatment (Rx), or TAILORx, had their breast tumors analyzed with a molecular test.

The second study tested a form of immunotherapy against chemo, in the most common lung cancer worldwide, known as non-small-cell lung cancer.

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